| Innate immunity | Adaptive Immunity |
|---|---|
| First line of defence | specific and efficient |
| Involves Natural Killer cells, macrophages neutrophils | Antigen presenting cell activates adaptive immunity |
| Clears ASAP but cannot always recognise pathogen | Soluble mediates - antibodies from B cells Cell mediated - t cells recognise |
Bcells differentiate in bone marrow → split into Plasma cells Tcells differentiate in thymus → can split into Helper T (CD4+), or Cytotoxic T (CD8+)